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Saskia Drijver-Headley1, Judith Godin2, Kenneth Rockwood2, Peter Hanlon3
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Background: Worldwide population ageing is motivating how to measure the health of ageing populations. One approach is to compare dynamics of frailty, assessed by the cumulative-deficit frailty index, across different populations. We aim to compare the frailty distribution, mortality risk, and change in frailty over time between 18 countries. Methods: Using data from five harmonised international surveys (HRS, SHARE, ELSA, CHARLS and MHAS) we assessed frailty with a 40-item frailty index (baseline, 2-, 4- and 6-year follow-up), along with mortality status. We constructed separate regression

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Peter Hanlon, Eric Bischoff, Jennifer Burton, Jordan Canning, Karen Wood, Rose Collard, Barbara Nicholl
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Introduction: People living with multiple long-term conditions (MLTC) are more likely to experience hospital admission, which is often associated with unintended consequences. Preventing or providing alternatives to admission by predicting adverse admission-related outcomes is important. This study aims to provide an overview of the association between MLTCs and adverse outcomes following hospital admission through a systematic review of systematic reviews. Method: We searched Medline, Embase, CINAHL, Web of Science and PsycINFO for systematic reviews assessing risk factors/predictors of

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Heather Wightman1, Elaine Butterly1, Lili Wei1, Ryan McChrystal1, Naveed Sattar2, Amanda Adler3, David Phillipo4, Sofia Dias5, Nicky Welton4, Andrew Clegg6, Miles Witham7,8, Kenneth Rockwood9, David McAllister1, Peter Hanlon1
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Introduction: The representation of frailty in type 2 diabetes trials is unclear. This study used individual patient data (IPD) from trials of newer glucose-lowering therapies to quantify frailty and assess the association between frailty and treatment efficacy and adverse events. Methods: We analysed IPD from 34 trials of sodium glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors. Frailty was quantified using a cumulative deficit frailty index (FI). For each trial we assessed the distribution of the FI; interactions between

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A Nelmes1; S Goodison1; R Monteith1; R Morse1
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Introduction The recent introduction of the Medical Examiner (ME) service changed the process for Medical Certificate of Cause of Death (MCCD) completion across Wales. This offered opportunity for local process redesign and embedding of team-based education and reflective practice, whilst reducing delays in MCCD completion for bereaved families. Methods We produced a process map and discussed with key stakeholders - ward teams, bereavement staff and the ME Office. We developed a team–based Proposed Cause of Death form (several PDSA Cycles) to prompt and stimulate early medical team discussion

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P Hanlon E Butterly L Wei H Wightman S Ali M Almazam K Alsallumi J Crowther R McChrystal H Rennison K Hughes J Lewsey R Lindsay S McGurnaghan J Petrie L A Tomlinson S Wild A Adler N Sattar D Phillippo S Diaz N Welton D McAllister
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Background: Newer glucose-lowering agents for type 2 diabetes (sodium glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor analogues (GLP1ra) and dipeptidyl peptidase-4 inhibitors (DPP4i)) improve hyperglycaemia and SGLT2i and GLP1ra reduce the risk of major adverse cardiovascular events (MACE). It is not clear whether the efficacy of these agents varies by age. Methods: We searched Medline and Embase, plus clinical trial registries, for randomised controlled trials of SGLT2i, GLP1ra and DPP4i, versus placebo or active comparator, in adults with type 2 diabetes

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Qi Zhang
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Introduction: The aging population has increased the demand for family caregivers, who often suffer from psychological distress, especially compassion fatigue. This systematic review and meta-analysis evaluate the effectiveness of web-based compassion interventions in improving the mental well-being of family caregivers. Methods: MEDLINE, Embase, PsycINFO, Web of Science, Cochrane Library, and Proquest were searched from database inception until manuscript submission date. Eligible studies included family caregivers participating in web-based compassionate interventions with reported mental

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Lester Coleman 1; Ekow Mensah 2; Khalid Ali 2, 3.
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Introduction As the prevalence of dementia continues to increase across the UK, understanding the lived experience of patients and carers affected by dementia becomes paramount. There is an established dementia pathway in Sussex for people living with dementia (PLWD) and their carers. To improve care and inform future commissioning priorities, the Brighton and Hove Health Watch (BHHW- a community interest company) surveyed the opinions of a group of PLWD and their carers around initial diagnosis and subsequent support. Methods PLWD and their carers receiving social support and willing to

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L Bown1; A Chandler2; R Male2; N Humphry2
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This service evaluation reviewed the impact of the Perioperative Care of Older People Clinic (POPS) on Anticholinergic Burden (ACB) in older surgical patients and identified areas for improvement. The study assessed 75 patients aged ≥65 years, revealing widespread anticholinergic use. Among patients on anticholinergics, 34% experienced a reduction in ACB post-POPS review. However, maintaining these changes at ≥6 months was challenging, with 50% of patients experiencing a change in their ACB score due to new prescriptions or the re-initiation of old medications. The study identified

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NJ Cox (1); SER Lim (1); AA Sayer (2,3); SM Robinson (2,3)
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Introduction Poor appetite affects 15-20% of community dwelling older adults. Studies link poor appetite with frailty and sarcopenia; however, lack of longitudinal evidence exists to inform potential causality. We aimed to determine if poor appetite predicts frailty or sarcopenia-related factors in community dwelling older adults. Methods Secondary data analysis on adults aged >60 years recruited from, syncope, fragility fracture and comprehensive geriatric assessment clinics with 2.5 year follow up. Appetite was assessed by Simplified Nutritional Appetite Questionnaire (SNAQ); a score of <14

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Xiaoting Huang; Kenneth Chua Wei De; Shirlene Moh Peh Shi; Heng Wai Yue; David Low Yong Min; Anaikatti Poongkulali; Arshad Iqbal; Barbara Helen Rosario
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Benign Paroxysmal Positional Vertigo (BPPV) is the most common cause of vertigo in older adults. Due to the high incidence of BPPV in older adults presenting with falls, vestibular assessment, and diagnosis of BPPV and other vestibular disorders has become a recommendation in the World Guidelines for Falls Prevention. There has been a paucity of evidence in well conducted randomised controlled trials (RCTs) to evaluate vitamin D for prevention of BPPV recurrence and its relation to falls and function. This is a Phase IIa single centre, placebo controlled, double blind RCT to evaluate vitamin D

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Dr Tillana Tarkas, Dr Yoganathan Suthahar
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Introduction National surveillance shows an estimated 58,224 people in England had antibiotic-resistant infections in 2022, a rise of 4% since 2021 (ESPAUR report). Between 2022-23, our Trust had 2 nd highest C.difficile rates in the country. Geriatric population is particularly vulnerable of inappropriate antimicrobial prescribing, leading to prolonged hospital stays As part of anti-microbial stewardship (AMS), a Quality improvement project was carried out between February-May 2024. Methods Six geriatric wards (n=168) were audited between 14-16 th February 2024. Indication, route, duration

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L Coleman 1; E Mensah 2; R Mukhopadhyay 2; K Ali 2,3.
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Introduction People from ethnic minorities are 1.5 times less likely to use digital technology. Within Brighton and Hove, 2021 Census reports that 26.1% described themselves as non-White-British categorised as other White (11.5%), Mixed Race (4.8%), Asian (3.7%), Black (2.0%), Chinese (1.1%), Arab (1.1%), and Other (2.0%). The aim of the project was to understand the lived experience of older ethnic minority adults in Brighton and Hove with digital technology, and how this experience affects their potential engagement with research. Methods Older people from ethnic minorities were identified

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Katriona Hutchison, John Hodge, Anthony Bishop, Sarah Keir
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Introduction Physical and cognitive frailty combined with unfamiliar surroundings in hospitals puts elderly patients at high risk of falls. It has been demonstrated that patient-centred, non-clinical stimulating activities in hospital have been found to reduce agitation, improve affect and engagement, relieve pressure on nursing staff and reduce falls. In the Medicine of the Elderly (MOE) wards of an urban teaching hospital, after a successful pilot, a Meaningful Activity Team (MAT) was implemented. The effect of this change to patient and staff well-being was assessed, as was the frequency of

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Dr U Ekwegh, Dr S Naylor
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INTRODUCTION: As part of a larger quality improvement project focused on improving the management of older people living with frailty attending the Manchester Royal Infirmary, a Frailty Same Day Emergency Care Unit (Frailty SDEC) was established. This would require the merging of three teams: the Front Door Frailty team, the Acute Therapy team and an established Nursing team on the allocated ward area. It became apparent that an intervention was required to improve team-working and efficiency among these clinicians who had never all worked together in the same space before. METHODS: Board

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Sarah Keir 1, IanMcClung 2, Laura Smith 1, Jo Cowell 1
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Introduction The Assessment and Rehabilitation Centre (ARC) in Edinburgh sees around 600 new patients a year who are beginning to demonstrate signs of frailty, principally around mobility and balance. When taking a comprehensive geriatric assessment, we commonly identify concerns around cognition. We noted in some cases people were already waiting to be seen by the Memory Clinic Services, the current wait for which is approximately 10 months. We decided to see what ARC could do to help. Method From within existing resources, alongside the Psychiatry of Older Age (POA) Team, the ARC multi

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E Littlewood1,2; H Baker1,2; E Agnew1,2; J Heeley1; L Atha1; D Bailey1; E Ryde1,2; L Shearsmith3; K Bosanquet1; S Crosland1; K Hollingsworth1; H Stevens1; K Webb1; P Coventry1; CA Chew-Graham4; D McMillan1,5; D Ekers1,2; S Gilbody1,5
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Background Older adults were more likely to be socially isolated during the COVID-19 pandemic, with increased risk of depression and loneliness. The Behavioural Activation in Social Isolation (BASIL+) trial investigated whether a Behavioural Activation (BA) intervention delivered remotely could mitigate depression and loneliness in at-risk older people during the COVID-19 pandemic. Methods We undertook a multicentre randomised controlled trial [ISRCTN63034289] of BA to mitigate depression and loneliness among older adults (65+) with multiple long-term health conditions, including low mood or

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Matt Hutchins, Sophie Maggs, Amara Williams, Devyani, K Vegad, Inder Singh
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Introduction: Fracture liaison services (FLS) aim to prevent secondary fractures by ensuring high-quality care to all patients with fragility fractures above 50 years. The standard recommendation by FLS Database (FLS-DB) is to identify 80% of the expected fragility fractures, commencing treatment for 50% and monitoring 80% at 16 weeks and 52 weeks. Methods: FLS team noted that only 18.4% (n=92) patients were followed at one-year of the total 875 patients identified in the year 2021 (National benchmark=22.3%). Whilst FLS team identified 42.6% (n=1649) patients in the year 2022, an 88% increase

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SKoushik1; SNagsayi2; LCoombe3; CAguirre4; MElfeky5
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Introduction/Background: Teamwork is very important in hospitals where the medical on-call team manage the stroke and thrombolysis alert calls. In addition to technical skills, human factors play a very significant role in meeting a target door-to-needle time. Aim: To improve door-to-needle time by improving human factors (leadership, understanding and delegation of roles and confidence in participation) and technical factors (quick NIHSS and efficient documentation of vital information on radiology request forms for urgent CT head). Method: We conducted 6 simulation-based training sessions

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A Steeves1; P Jarrett1,2; K Faig1; CC Tranchant3; G Handrigan3; L Witkowski4; J Haché4; K MacMillan1; A Gullison5; H Omar1; C Pauley1; A Sexton5; CA McGibbon5,6
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Introduction: Research suggests that physical and cognitive exercise can have a positive effective on those with dementia, but less is known about such interventions in those at risk for dementia. Understanding the feasibility of administering clinical assessments remotely using Zoom for Healthcare TM in the context of a dementia prevention trial for at risk older adults is not well understood. Methods: SYNERGIC@Home/SYNERGIE~Chez soi (NCT04997681) is a home-based, remotely delivered clinical trial targeting older adults at risk for dementia. Participants underwent a screening/baseline

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K Chin; G Watson; A Paveley; H Dulson; L Thompson; R Schiff
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Introduction: CGA is the gold-standard intervention for older adults living with frailty. A challenge is providing person-centred, time-efficient CGA. The CGA-questionnaire (CGA-Q) aims to facilitate person-centred CGA, allowing patients/carers to highlight concerns. We describe a two-site multi-cycle QIP implementing the CGA-Q. Methods: CGA-Q is a 19-item questionnaire covering seven CGA domains. It was adapted from the validated CGA-GOLD questionnaire. Between March 2023-June 2024, CGA-Q was established in a London and Scottish NHS Trust using ‘Plan-Do-Study-Act’ methodology. Cycle 1-3

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